"How reliable is the 2021 Mercedes-Benz Sprinter 2500?"

"Based on 73 NHTSA complaints, the 2021 Mercedes-Benz Sprinter 2500 has a median complaint mileage of 11600 miles. The most common issue is FORWARD COLLISION AVOIDANCE: AUTOMATIC EMERGENCY BRAKING."

"What are common problems with the 2021 Mercedes-Benz Sprinter 2500?"

"The most frequently reported component in NHTSA complaints for the 2021 Mercedes-Benz Sprinter 2500 is FORWARD COLLISION AVOIDANCE: AUTOMATIC EMERGENCY BRAKING, accounting for a significant portion of the 73 total complaints filed."

2021 Mercedes-Benz Sprinter 2500: Reliability Data

Source: NHTSA — 73 complaints

Total Complaints

11,600mi

Median Mileage

FORWARD COLLISION AVOIDANCE: AUTOMATIC EMERGENCY BRAKING

Top Issue

Crash Reports

When Do Complaints Happen?

Distribution of NHTSA complaints by vehicle mileage at time of report.

1,100 25th Percentile

11,600 Median Mileage

20,000 75th Percentile

What Fails?

Most reported component issues from NHTSA complaints.

FORWARD COLLISION AVOIDANCE: AUTOMATIC EMERGENCY BRAKING

ELECTRICAL SYSTEM

UNKNOWN OR OTHER

SERVICE BRAKES

ENGINE

POWER TRAIN

LANE DEPARTURE: ASSIST

FORWARD COLLISION AVOIDANCE: WARNINGS

FUEL/PROPULSION SYSTEM

FORWARD COLLISION AVOIDANCE: ADAPTIVE CRUISE CONTROL

Severity Assessment

Crashes

Fires

Injuries

Deaths

Sample Complaint Reports

"2021 MERCEDES BENZ SPRINTER CARGO VAN. CONSUMER WRITES IN REGARD TO BLUETOOTH SYSTEM. *LD THE CONSUMER STATED THE FEATURE USED TO ANSWER A CELLPHONE VIA BLUETOOTH WAS A SAFETY HAZARD. *JS*DT"

"Delivery driver parked at top of customer's driveway. Driver placed van in park and engaged the ebrake. Driver went to rear of vehicle, retrieved customer's package, and exited the van. Driver was handing customer the package when the driver and customer heard clicking sounds coming from van. Va..."

"The contact owns a 2021 Mercedes-Benz Sprinter 2500. The contact received notification of NHTSA Campaign Number: 21V411000 (Electrical System, Back Over Prevention) however, the part to the recall repair was unavailable. The contact took the vehicle to the local dealer and it was confirmed that the ..."

Source: NHTSA ODI Complaints Database. Names and identifying details omitted.

Data source: View this vehicle on NHTSA.gov | NHTSA ODI Complaints Database. Public domain.

Methodology: Complaint counts and mileage distributions are computed directly from consumer-reported NHTSA complaints. This data represents reported issues, not failure rates — vehicles without complaints are not represented. Full methodology.

Data through: 2026-03-28