How Long Does Zepbound Last?

Generic: TIRZEPATIDE

30 days
Shelf life from federal drug label data

Storage Conditions

Room temperature Refrigerate Do not freeze Protect from light

Manufacturer

Eli Lilly and Company

Storage Information

16.2 Storage and Handling Do not freeze ZEPBOUND. Do not use ZEPBOUND if frozen. Protect ZEPBOUND from heat and light. Store ZEPBOUND in the original carton to protect from light. ZEPBOUND Single-dose Pen and Single-dose Vial Store ZEPBOUND single-dose pen and single-dose vial in a refrigerator at 2°C to 8°C (36°F to 46°F). If needed, each single-dose pen or single-dose vial can be stored unrefrigerated at temperatures not to exceed 30°C (86°F) for up to 21 days. If single-dose pen or single-dose vial is stored at room temperature, it should not be returned to the refrigerator. Discard single-dose pen and single-dose vial if not used within 21 days after removing from the refrigerator. ZEPBOUND Multi-dose Vial or Single-Patient-Use KwikPen Unopened vial or single-patient-use KwikPen: Store unopened multi-dose vial or single-patient-use KwikPen in the refrigerator at 2°C to 8°C (36°F to 46°F). The unopened multi-dose vial or single-patient-use KwikPen can be used until the expiration date on the label if kept in the refrigerator. If stored at room temperature [up to 30°C (86°F)], throw away unopened multi-dose vial or single-patient-use KwikPen after 30 days. After vial or single-patient-use KwikPen has been opened: Store opened (in-use) multi-dose vial or single-patient-use KwikPen in the original carton in the refrigerator at 2°C to 8°C (36°F to 46°F) or at room temperature [up to 30°C (86°F)]. Throw away opened multi-dose vial or single-patient-use KwikPen after a total of

Important: This information is from federal drug label data and is for reference only. Always follow the specific expiration date printed on your medication packaging. Consult your pharmacist or healthcare provider with questions about medication storage or expiration.

Data source: View Zepbound on DailyMed (NIH) | Federal drug label data.

Last verified: 2026-03-28