How Long Does Insulin Lispro Last?
Generic: INSULIN LISPRO
Source: Federal Drug Label Data
28 days
Shelf life from federal drug label data
Storage Conditions
Room temperature
Refrigerate
Do not freeze
Protect from light
Manufacturer
Eli Lilly and Company
Storage Information
16.2 Storage and Handling Dispense in the original sealed carton with the enclosed Instructions for Use. Protect from direct heat and light. Do not freeze and do not use if it has been frozen. See table below for storage information: * When stored at room temperature, Insulin Lispro can only be used for a total of 28 days, including both not in-use (unopened) and in-use (opened) storage time. Not In-Use (Unopened) Room Temperature (Up to 86°F [30°C]) Not In-Use (Unopened) Refrigerated (36° to 46°F [2° to 8°C]) In-Use (Opened) (see temperature below*) 10 mL multiple-dose vial 28 days Until expiration date 28 days Refrigerated or room temperature. 3 mL single-patient-use Insulin Lispro KwikPen 28 days Until expiration date 28 days Room temperature only (Do not refrigerate) 3 mL single-patient-use Insulin Lispro Junior KwikPen 28 days Until expiration date 28 days Room temperature only (Do not refrigerate) Use in an External Insulin Pump — Change the Insulin Lispro in the reservoir at least every 7 days, or according to the pump user manual, whichever is shorter, or after exposure to temperatures that exceed 98.6°F (37°C). Storage of Diluted Insulin Lispro for Subcutaneous Injection — Diluted Insulin Lispro for subcutaneous injection may be stored for 28 days when refrigerated at 41°F (5°C) and 14 days at room temperature up to 86°F (30°C) [see Dosage and Administration ( 2.2 )] . Do not dilute Insulin Lispro used in an external insulin pump. Storage of Intravenous Infusion Prep
Important: This information is from federal drug label data and is for reference only. Always follow the specific expiration date printed on your medication packaging. Consult your pharmacist or healthcare provider with questions about medication storage or expiration.
Data source: View Insulin Lispro on DailyMed (NIH) | Federal drug label data.
Last verified: 2026-03-28
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