How Long Does Humalog Mix50/50 KwikPen Last?

Generic: INSULIN LISPRO

28 days
Shelf life from federal drug label data

Storage Conditions

Room temperature Refrigerate Do not freeze Protect from light

Manufacturer

Eli Lilly and Company

Storage Information

16.2 Storage and Handling Dispense in the original sealed carton with the enclosed Instructions for Use. Protect from direct heat and light. Do not freeze and do not use if it has been frozen. See storage table below: a When stored at room temperature, HUMALOG Mix50/50 vial can only be used for a total of 28 days including both not in use (unopened) and in-use (opened) storage time. b When stored at room temperature, HUMALOG Mix50/50 KwikPen can only be used for a total of 10 days including both not in-use (unopened) and in-use (opened) storage time. Not In-Use (Unopened) Refrigerated (36° to 46°F [2° to 8°C]) Not In-Use (Unopened) Room Temperature (up to 86°F [30°C]) In-Use (Opened) (see temperature below) 10 mL multiple-dose vial a Until expiration date 28 days 28 days Refrigerated or room temperature 3 mL single-patient-use KwikPen b prefilled pen Until expiration date 10 days 10 days Room temperature only (Do not refrigerate)

Important: This information is from federal drug label data and is for reference only. Always follow the specific expiration date printed on your medication packaging. Consult your pharmacist or healthcare provider with questions about medication storage or expiration.

Data source: View Humalog Mix50/50 KwikPen on DailyMed (NIH) | Federal drug label data.

Last verified: 2026-03-28